Melatonin is a potential drug for the prevention of bone loss during space flight

Melatonin could be a novel drug for preventing bone loss to astronauts during space flight. Here we used goldfish scales as a bone model of coexisting osteoclasts and osteoblasts and demonstrated that melatonin synthesis decreased under microgravity. Melatonin treatment of scales stimulated expression of Calcitonin, an osteoclast-inhibiting hormone, and decreased expression of an osteoclastogenesis promotor. This is the first study to report the inhibitory effect of melatonin on osteoclast activation, which is cancelled by microgravity.

from http://besthealthnews.com/2019/09/melatonin-is-a-potential-drug-for-the-prevention-of-bone-loss-during-space-flight/?utm_source=rss&utm_medium=rss&utm_campaign=melatonin-is-a-potential-drug-for-the-prevention-of-bone-loss-during-space-flight

from
https://healthnews010.tumblr.com/post/187481836978

from https://johnher1.blogspot.com/2019/09/melatonin-is-potential-drug-for.html

from
https://johnher10.tumblr.com/post/187481940077

From https://stevenbrown1.blogspot.com/2019/09/melatonin-is-potential-drug-for.html

from
https://stevenbrown11.wordpress.com/2019/09/04/melatonin-is-a-potential-drug-for-the-prevention-of-bone-loss-during-space-flight/